...In 1790 Ferdinand married his double first cousin, the Princess (later Grand Duchess) Luisa of Naples and Sicily (27 July 1773, Naples - 19 September 1802, Vienna), daughter of Ferdinand I of the Two Sicilies and Marie Caroline of Austria. (She was one of 18 children, seven of whom survived to adulthood.) They had five children together, the first two dying very young. The Grand Duchess herself died while giving birth to her sixth child, a stillborn son; she was only 29. Nineteen years later, her husband remarried. His new, much younger bride - a first cousin once removed to both Ferdinand and his late wife - was Princess Maria Ferdinanda of Saxony. There were no children born of this marriage. (http://godsandfoolishgrandeur.blogspot.nl/2014/12/the-grand-duke-and-grand-duchess-of.html)