The Sisters1894-1895 by James Abbott McNeill Whistler

...Whistler's relationship began to suffer in 1879, when the artist went bankrupt and was forced to face reality. When he suddenly proposed to Beatrix Godwin in 1888—a marriage that would provide him with stability, order, and favorable connections—it may have been that the opportune moment had finally presented itself after years of mounting discomfort.

In his marriage to Beatrix, Whistler seems to have attained the harmony that he had been courting in his watercolors. The wistful depictions of Maud in solitude are replaced by accounts of Beatrix and her sisters delighting in domestic bliss, though it would not last long. Hints of Beatrix’s terminal cancer surface in lithographs such as The Sisters—all would be well in this interior if it were not for Beatrix’s languishing posture. She appears weak beside her upright sister, and there is an air of concern polluting the peaceful scene.
[https://www.freersackler.si.edu/almost-perfect-maud-franklin-and-whistlers-wistful-impressions]
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